1. Why is Overall Survival (OS), in months, represented as both a single number AND as a range?

2. Which treatment, Apatinib or placebo, resulted in better PFS (Progression-Free Survival)?

3. Why do you think the difference in ORR (overall response rate) between Apatinib and placebo didnt achieve statistical significance (p=0.1695)?

Table 2. Analysis of Efficacy in Full Analysis Set Apatinib (n = 176) Variable P Placebo (n = 91) 78 146 4.7 (3.6 to 5.4) 6.5 (4.8 to 7.6) 0.709 0.537 to 0.937) .0149 .0156 Death, No. OS Median (95% CI), months HR (95% CD PFS Disease progression or death, No. Median (95% CI), months HR (95% CD Response ORR, % 117 2.6 2.0 to 2.9 0.444 0.331 to 0.595) 79 1.8 (1.4 to 1.9) <.001 .1695 .55327 dcr abbreviations: disease control rate hr hazard ratio orr overall response os survival pfs progression-free survival. assessed by investigators. tassessed an independent evaluation committee. table analysis of efficacy in full set apatinib variable p placebo to .0149 .0156 death no. median ci months cd progression or committee>