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15. (EXTRA PROBLEM, you do not need to hand this in) In order to study if pro- longed exposure to ozone can cause DNA methylation

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15. (EXTRA PROBLEM, you do not need to hand this in) In order to study if pro- longed exposure to ozone can cause DNA methylation in two genomic locations, a randomized study was conducted. In the study reported by R. B. Devlin et al. (2012) healthy young volunteers participated. In the study randomlyselected 10 participants out of 17 were exposed for 2 hr, either to 0.3 ppm ozone or to cleanair. On Canvas you will find a file named "ozoneexperiment.csv" including data from thisstudy. In this table CA means clear air, O3 means ozone, exposure 0 means no exposureto ozone and 2 means exposure to ozone for 2 hrs. Finally, cg20129242 4 and cg21036194 are columns with outcome measures on DNA methylation in two genome locations with those names. Use this data and the R code inference_of_a_randomized_experiment.R to per- form two analyses for the hypotheses that there are no differences in DNA methy- lation between exposure toclean air and to ozone in the two genome locations cg20129242 and cg21036194. 15. (EXTRA PROBLEM, you do not need to hand this in) In order to study if pro- longed exposure to ozone can cause DNA methylation in two genomic locations, a randomized study was conducted. In the study reported by R. B. Devlin et al. (2012) healthy young volunteers participated. In the study randomlyselected 10 participants out of 17 were exposed for 2 hr, either to 0.3 ppm ozone or to cleanair. On Canvas you will find a file named "ozoneexperiment.csv" including data from thisstudy. In this table CA means clear air, O3 means ozone, exposure 0 means no exposureto ozone and 2 means exposure to ozone for 2 hrs. Finally, cg20129242 4 and cg21036194 are columns with outcome measures on DNA methylation in two genome locations with those names. Use this data and the R code inference_of_a_randomized_experiment.R to per- form two analyses for the hypotheses that there are no differences in DNA methy- lation between exposure toclean air and to ozone in the two genome locations cg20129242 and cg21036194

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