1.a)Mention the Significance/s of microbial biodegradation of xenobiotices. what is the importance of biomass utililization.Outline a strategy for enhancing the production of amino acid tryptophan by genetic engineering. b)Discuss the production of L-ascorbic acid.What are the limitations of synthesis of L-Ascorbic acid by cotransformation/ cocultivation with suitable organisms? c)How would you engineer yeast strain (recombinant yeast) to more efficiently convert glucose into ethanol? Discuss in detail. d)Hemoglobin in blood is suspected to be a sufferer of sickle cell anemia. Describe how the change in the human B-globin gene that gives rise to sickle-cell anemia