1.The following are body mass index (BMI) scores measured in 12 patients who are free of diabetes and are participating in a study of risk factors for obesity. Body mass index is measured as the ratio of weight in kilograms to height in meters squared. Generate a 95% confidence interval estimate of the true BMI.

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2.How many subjects would be needed to ensure that a 95% confidence interval estimate of BMI had a margin of error not exceeding 3 units?

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3.Peak expiratory flow (PEF) is a measure of a patient's ability to expel air from the lungs. Patients with asthma or other respiratory conditions often have restricted PEF. The mean PEF for children free of asthma is 306. An investigator wants to test whether children with chronic bronchitis have restricted PEF. A sample of 50 children with chronic bronchitis is studied, and their mean PEF is 251 with a standard deviation of 71. When you run the appropriate test at= 0.05, the appropriate conclusion to whether there statistical evidence of a lower mean PEF in children with chronic bronchitis is?

4.Peak expiratory flow (PEF) is a measure of a patient's ability to expel air from the lungs. Patients with asthma or other respiratory conditions often have restricted PEF. The mean PEF for children free of asthma is 306. An investigator conducts a study to investigate whether there is a difference in mean PEF in children with chronic bronchitis as compared to those without asthma or other respiratory conditions that often have restricted PEF. Data on PEF are collected and summarized below. Based on the data, is there statistical evidence of a lower mean PEF in children with chronic bronchitis as compared to those without? Run the appropriate test at= 0.05.

Group

Number of Children

Mean PEF

Std Dev PEF

Chronic Bronchitis

25

274

59

No Chronic Bronchitis

25

317

73

5.A clinical trial is run to investigate the effectiveness of an experimental drug in reducing preterm delivery to a drug considered standard care and to a placebo. Pregnant women are enrolled and randomly assigned to receive either the experimental drug, the standard drug or a placebo. Women are followed through delivery and classified as delivering preterm (< 37 weeks) or not. The data are shown below.

Preterm Delivery

Experimental Drug

Standard Drug

Placebo

Yes

15

23

40

No

83

79

67

Is there a statistically significant difference in the proportions of women delivering preterm among the three treatment groups? Run the test at a 5% level of significance.