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2. Aclinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study
2. Aclinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving seven participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later. Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of significance. Baseline: 120 145 130 160 152 143 126 4 Weeks: 122 142 135 158 155 140 130 Suggestions for computing the answer: Difference -2 3 -5 2 -3 3 -4 SDifferences =-6 Difference? 4 9 25 4 9 9 16 SDifferences? = 76 Step 1. Set up hypotheses and determine level of significance. Step 2. Select the appropriate test statistic. Step 3. Set up decision rule: Reject Hp if t
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