2. Consider the unfolding of a protein: Folded Unfolded H=120kJ/mol 2.1. Suppose the protein unfolds at 75C. Estimate S ? (Hint: At the unfolding temperature, the above reaction becomes spontaneous.) 2.2. Assuming the protein has only one way to be folded, how many ways are there for the protein to be unfolded? Equivalently, assuming the "folded" state corresponds to one microstate, how many microstates are grouped together and called the "unfolded" state. 2.3. A mutation to the protein adds two additional hydrogen bonds that must be broken for the protein to unfold. Assuming the hydrogen bonds each have a strength of 11kJ/mol, what do you predict for the value of the temperature at which the protein unfolds? (Assume the mutation has no effect on the entropies of the folded and unfolded state.)