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2. Explain the concepts: a) Sample matrix. b) Matrix interference. c) External standard. d) Internal standard. e) Calibration curve. (5p) 3) Liquid chromatography a) Explain

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2. Explain the concepts: a) Sample matrix. b) Matrix interference. c) External standard. d) Internal standard. e) Calibration curve. (5p) 3) Liquid chromatography a) Explain how an HPLC instrument is structured? Make a sketch the instrumentation. (3p) b) Make a sketch of the injector and explain how the sample introduction is performed in HPLC? (3p) c) Explain what is meant by isocratic elution and gradient elution. Provide benefits and disadvantages of the two methods

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