2. In a randomized clinical trial to determine the most effective timing of the administration of chemotherapeutic drugs to lung cancer patients, 26 patients were given four drugs simultaneously, while 15 patients were given the same four drugs sequentially. Objective response to the treatment (defined as the shrinkage of the tumor by at least 50%) was observed in 16 of the patients treated simultaneously and in 4 of the patients treated sequentially. Assuming their data was from a random sample with independent observations, carry out the appropriate test to determine if there is a difference in effectiveness between the two different treatments. Include all steps for full credit. Given: critical value = 3.84 (6pt)