2 When a sample is less than 60, it is appropriate to computing the standard error of the mean when O subtract 1 from n O add 1 to n O estimate the margin of error O caculate the confidence interval Question 42 2 pts A general statistical rule states that a distribution of means from large samples will most likely have a normal shape O will not likely be skewed will less likely vary from the mean O will not be greater than 3 standard deviations