Question
25. What is the primary defect in chronic granulomatous disease (CGD)that leads to increased susceptibility to infection? A) Deficiency of NADPH oxidase enzyme B) Decreased
25. What is the primary defect in chronic granulomatous disease (CGD)that leads to increased susceptibility to infection?
A) Deficiency of NADPH oxidase enzyme
B) Decreased respiratory burst in neutrophils
C) Reduced glucose utilization by neutrophils
D) Increased activation of complement
26. Which cells are affected by leukocyte adhesion deficiency?
A) T cells
B) B cells
C) Neutrophils
D) Macrophages
27. What is the characteristic manifestation of Job's syndrome?
A) Hepatosplenomegaly and pneumonia
B) Presence of large lysozomal granules in leukocytes
C) Repeated staphylococcal abscesses and eczema
D) Absence of decay-accelerating factor (DAF) on blood cell precursors
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