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3) A given non-ionic iodinated contrast agent follows one compartment pharmacokinetics. K12 If the drug half-life is 17 hours and the apparent volume of
3) A given non-ionic iodinated contrast agent follows one compartment pharmacokinetics. K12 If the drug half-life is 17 hours and the apparent volume of distribution is 19 L, i. Calculate the IV infusion necessary to achieve a steady state concentration of 15 mg/mL. ii. What IV bolus loading dose would you use to achieve 15 mg/mL rapidly? iii. What IV infusion rate would you need to get to 15 mg/mL in 30 minutes?
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