3. A medical researcher establishes that a patient's reaction time, r, in minutes, to a dose of a particular drug is r (d) = - 0.8d3 + da, where d is the amount of the drug, in millilitres, that is absorbed into the patient's blood. Determine the instantaneous rate of change of the time reaction with respect to the amount of the drug at 1 millilitre. /4-A MHF 4U1 Name: Period: 4. Boxes for candies are to be constructed from cardboard sheets that measure 36 cm by 20 cm. Each box is formed by folding a sheet along the dotted lines, as shown. What are the possible whole number dimensions of the box if the volume is to be 512 cm3? /5-T 20 cm K 36 cm 5. Explain how the sign of the leading coefficient of an even degree polynomial function impacts the functions end behaviours. /3-C