Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

3. Insulin is a multipeptide hormone that is released in response to high blood glucose levels thereby regulating the metabolism of carbohydrates, fats, and proteins.

image text in transcribed
3. Insulin is a multipeptide hormone that is released in response to high blood glucose levels thereby regulating the metabolism of carbohydrates, fats, and proteins. Shown below a ribbon representation of the 3D structure as well as a pictorial representation of the primary sequence (PDB = 1trz). Answer the following questions about this peptide. [ 30pts.] a) Draw the chemical structure of the last eight amino acids in the B chain in the correct protonation state. \{Note: Make sure not to ignore stereochemistry.\} b) Of the amino acids you drew in part a, identify the most acidic side chain and calculate the protonation state (\% protonated, % deprotonated) at a physiologically relevant pH. c) of the amino acids you drew in part a, identify the most basic side chain and calculate the protonation state (\% protonated, \% deprotonated) at a physiologically relevant pH

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Organic Chemistry

Authors: Paula Yurkanis Bruice

4th edition

131407481, 978-0131407480

More Books

Students also viewed these Chemistry questions

Question

6. Issues in the long term

Answered: 1 week ago