1. *(3 total points, see *s below) Reread the article Surprise! Hydroxychloroquine Worked in New Michigan Study, which are in the Peoples Pharmacy on July 3, 2002. You read this article for homework assignment #1. Use the (Revised) Guidelines for Study Evaluation that were used for the Week 5 Discussion to evaluate this article. Briefly comment on the study quality, interpretation and the reporting done by the Peoples Pharmacy of the Michigan study. Your answers can be listed as bullet points.

Study quality

• *(1 point) What is the study design?

• Are the measures or outcomes well-defined?

• *(1 point) Are estimates of relative or absolute risks reported and/or can either type of risk be determined? Or, if the outcome is quantitative, are estimates of the relative or absolute difference reported and/or can they be determined?
• Is the uncertainty of the study estimates/results reported?

• Has the study been peer reviewed?

• What was the size of the study?

Interpretation

• *(1 point) Are alternative explanations provided?

• What is the appropriate target population to which the results can be generalized?

• Is it a primary, secondary or exploratory analysis?

Reporting

• Are other studies in this area mentioned?

• Is there independent comment?

• Who conducted and paid for the study?

• Is headline accurate?