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4) Enzymes can also be used to produce a single enantiomer with high optical purity. Read the paper Production of S-(+)-Ibuprofen from a Nitrile

4) Enzymes can also be used to produce a single enantiomer with high optical purity. Read the paper "Production of S-(+)-Ibuprofen from a Nitrile Compound by Acinetobacter sp. Strain AK226" by Yamamoto, et al., and answer the following questions. io CN H propiontie NAIME Sicrobuprotes COOM R5214 sobutypheny@propionitrie a) As a process chemist it is important to pick the optimal conditions that will produce the desired product in highest vield and that minimize the by products. If you are the process chemist, what bacterial strains would you eliminate from your study to produce S-(+)- ibuprofen? Give a reason for your choices. b) How was S-(+)-ibuprofen isolated from the reaction mixture in this paper? This is NOT the purification process HICH The specific rotation reported for S-(*)-ibuprofen in this paper was +54.00 (c 95% ethanol) If they had found instead a specific rotation of -34.00 (c-1.95% ethanol) what is the composition of mixture for this sample" Show your work to get eredit Please use the "reported specific rotation" used in the paper for their calculations You have to read the paper to find this

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