4.

Suppose a randomized trial estimates that a new flu vaccine is associated with a 10% reduction in absolute risk as compared to the current standard vaccine, with a 95% CI (-0.13, -0.07). How could this confidence interval be expressed in terms of the potential impact of the new vaccine?

a. After accounting for sampling variaiblity, if the new vaccine were given to 1,000 persons (from the same population as the study sample), we would expect to see 70 to 130 more flu cases, than if the 1,000 persons were given the standard vaccine.

b. After accounting for sampling variaiblity, if the new vaccine were given to 1,000 persons (from the same population as the study sample), we would expect to see 70 to 130 fewer flu cases, than if the 1,000 persons were given the standard vaccine

c. ndividuals given the new vaccine have between 7 to 13 lower relative risk of contracting the flu as compared to individuals given the standard vaccine.

d. Individuals given the new vaccine have between 7 to 13 greater relative risk of contracting the flu as compared to individuals given the standard vaccine.