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4. When nucleophilic attack of carbonyls undergo nucleophilic addition under acidic conditions the reaction can proceed past the hemiacetal to for the acetal. This involves

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4. When nucleophilic attack of carbonyls undergo nucleophilic addition under acidic conditions the reaction can proceed past the hemiacetal to for the acetal. This involves collapse of the tetrahedral intermediate and kicking out a leaving group. What are the three structural features that can help make a good leaving group? Use drawings to highlight each feature. a. Feature 1 b. Feature 2 c. Feature 3

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