5. (15) For a clinical trial, 20 patients were randomized according to allocation ratio 1:3 (A vs. B). They are listed below in the order
5. (15) For a clinical trial, 20 patients were randomized according to allocation ratio 1:3 (A vs. B). They are listed below in the order they were randomized. Prior to randomization the investigators noted whether the surgery being performed was high or low-risk for a surgical site infection based on other data. Suppose the random numbers sequence obtained is 990870493 390390417952987346529410897324. Patient No. High/Low. 1 High 2 High 3 Low 4 Low 5 High 6 High 7 High 8 High 9 High 10 Low 11 High 12 High 13 High 14 Low 15 Low 16 Low 17 Low 18 High 19 Low 20 Low b. Use the block randomization schedule to determine the treatment assignment for these 20 patients and give the number and percent in each treatment group that were scheduled for high risk surgery. c. Prepare randomization schedules for a stratied design (low and high risk surgery) and after you have done that, determine the treatment assignments for the 20 patients shown above, give the number assigned each treatment and the number and percent in each treatment group that were scheduled for high risk surgery. a. Use the simple randomization schedule to determine the treatment assignment for these 20 patients and give the number and percent in each treatment group that were scheduled for high risk surgery
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