6. Rapid antigen-based COVID-19 tests provide faster results than the gold standard PCRbased COVID-19 tests; however, it is important to determine whether they have the same accuracy. Individuals experiencing COVID-19 symptoms were recruited to a study evaluating the rapid tests. The PCR-based test was used to diagnose true COVID-19 cases. Of those individuals with a confirmed COVID-19 diagnosis based on the PCR test, 72% were correctly identified as having COVID-19 using the rapid test. Of those individuals who did not have COVID-19 based on the PCR test, 99.5% were correctly identifed as not having COVID-19 using the rapid test. Which of the following statements is true about the performance of the rapid antigen test for COVID-19? (Assume that the PCR test always gives the correct result.)

A) False negative rate=0.5% and we do not have enough information to compute NPV

B) False positive rate=28% and we do not have enough information to compute PPV

C) Sensitivity=72% and False negative rate=28%

D) Sensitivity=99.5% and False negative rate=0.005% E) Specificity=99.5% and False positive rate=28%