Question: 7. Suppose a mutation changes a codon in a gene from GTA (or GUA in mRNA) to GAA. What is the corresponding amino-acid change?

7. Suppose a mutation changes a codon in a gene from GTA (or GUA in mRNA) to GAA. What is the corresponding9. Examine the BLOSUM62 substitution matrix and list 3 amino acid pairs that are more likely to replace each

7. Suppose a mutation changes a codon in a gene from GTA (or GUA in mRNA) to GAA. What is the corresponding amino-acid change? What are two ways in which this small change in DNA could produce a drastic change in the function of the protein encoded by this gene? 8. Suppose a gene's coding region begins with the sequence ATGCTCCGGCAAAGG. A gene in another organism begins with the sequence ATGTTAAGAAACCGT, so there does not seem to be much sequence similarity. Is it likely that these two genes encode proteins of similar functions? (Hint: Translate the sequences before answering the question.) 9. Examine the BLOSUM62 substitution matrix and list 3 amino acid pairs that are more likely to replace each other in a protein sequence with a positive score. Give examples of amino acids that are the least likely to be replaced by another amino acid in a protein?

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GUA codes for Valine and GAA codes for glutamic acid So the mutation changes the corresponding amino ... View full answer

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