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A bioreactor hosts a genetically improved cell strain of B . lactofermentum to convert glucose to glutamic acid ( C 2 H 9 NO 4

A bioreactor hosts a genetically improved cell strain of B. lactofermentum to convert glucose to glutamic
acid (C 2 H9 NO4) for production of MSG and other products. The cells metabolize glucose according to
the following balanced chemical reaction:
C 6 H12 O6(s)+ NH3(g)+1.5O2(g) C5 H9 NO4(l)+3H2O(l)+ CO2(g)
The liquid-phase inlet stream contains water and glucose; the mass fraction of glucose is 0.05. The liquid
phase inlet flow rate is 200 kg/hr. The liquid flow rate of the unreacted glucose is 2.0 kg/hr. Ammonia
and oxygen enters in a separate gas phase stream. Carbon dioxide as well as excess ammonia and oxygen
leave in a second gas phase product stream.
The system is operated continuously, and reaction products and excess reactants are removed such that no
accumulation occurs. The inlet and outlet streams are at 25\deg C.
What rate of heat should be added or removed from the system to maintain the bioreactor at a
steady temperature? Report your answer in kJ/hr.
Standard heats of formation:
Glutamic Acid: -1011.6 kJ/mol
Glucose: -1274 kJ/mol
CO2 : -394 kJ/mol
H2 O: -286 kJ/mol
NH3 : -46.11 kJ/mol

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