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A case-control study was conducted to determine whether use of the anti-nausea drug Bendectin was associated with an increased risk of birth defects. Cases were

A case-control study was conducted to determine whether use of the anti-nausea drug Bendectin was associated with an increased risk of birth defects. "Cases" were mothers whose children had been born with birth defects; controls consisted of mothers of similar age and socioeconomic status who had children without birth defects. Cases and controls were selected by the same mechanism. Information about drugs taken during pregnancy was obtained from the list of prescribed medications on the maternal medical record.

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