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A certain fraction of antibiotics injected into the bloodstream are bound to serum proteins. This is a phenomenon of considerable pharmacological importance, because as the
A certain fraction of antibiotics injected into the bloodstream are "bound" to serum proteins. This is a phenomenon of considerable pharmacological importance, because as the extent of binding increases, the systemic uptake of the drug decreases. This, in turn, bears directly on the effectiveness the medication will ultimately have. In one recent study, determinations were made of the binding percentages characteristic of five widely used antibiotics. Bovine (MOO MOO) serum was used in each instance, but the results are comparable to what could be expected in human serum. Penicillin Tetracyclin Streptomyci Erythromyci Chloramph 29.6 27.3 5.8 21.6 29.2 24.3 32.6 6.2. 17.4 32.8 28.5 30.8 11 18.3 25 32 34.8 8.3 19 24.2 y = 114.40 125.50 31.30 76.30 111.20 ww = 3302.9 3967.7 261.97 1465.2 3139.1 Your job is to a) complete the ANOVA table, b) Calculate the F and test the global hypothesis (Use a =.05 ) Source df SS MS F Between Within 135.82 Total 1616.65 1 Ho: H: 5.Decision: (Circle one} Reject He or Fail to Reject Ho 2 = 6. P-value 3 Critical Value 7.Statement: 4 Test stat Profit Margin (Return on Sales) is calculated as: Select one: O A. Contribution Margin / Sales B. Sales / Operating Income C. Operating Income / Sales O D. Sales / Contribution Margin E. None of the above
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