A clinical trial was conducted to test the effectiveness of the drug caddelockess for treating migraines in older subjects. Before treatment with caddelockess , 25 subjects had a mean headache time of 114.3 minutes. After treatment with caddelockess , the 25 subjects had a mean headache time of 97.5 minutes and standard deviation of 39.2 minutes. Assume that the 25 sample values appear to be from a normally distributed population and construct a 99% confidence interval estimate of the mean headache time for a population with caddelockess treatments. What does the result suggest about the mean headache time of 114.3 minutes before the treatment? Does caddelockess appear to be effective?