A cohort study examined the association between exposure to high stress occupations and the risk of heart disease. Smoking was identified as a potential confounder in this study.

Below is the output from OpenEpi for crude and adjusted effect estimates. Using the output below answer questions 41-44.

Risk-Based* Estimates and 95% Confidence Intervals (Not valid for Case-Control studies) Point Estimates Confidence Limits Stratum Type Value Lower, Upper Type 1 Risk in Exposed 1% 0.0, 21.14 Taylor series Risk in Unexposed 4% 0.3416. 14.22 Taylor series Overall Risk 4% 0.9018, 11.58 Taylor series Risk Ratio 1 0.0952, 10.51 Taylor series Risk Difference 0.0 -9.407, 9.407 Taylor series 2 Risk in Exposed 52% 38.51, 65.2 Taylor series Risk in Unexposed 38.71% 23.69, 56.22 Taylor series Overall Risk 46.91% 36.43, 57.67 Taylor series Risk Ratio 1.343 0.8012, 2.2521 Taylor series Risk Difference 13.29% -8.748, 35.33 Taylor series Crude Risk in Exposed 36% 26.04, 47.32 Taylor series Risk in Unexposed 17.28% 10.46, 27.07 Taylor series Overall Risk 26.28% 19.98, 33.72 Taylor series Risk Ratio 2.083 1.185, 3.6611 Taylor series Risk Difference 18.72% 5.086, 32.350 Taylor series Etiologic fraction in pop.(EFp) 34.24% 9.541, 58.93 Etiologic fraction in exposed(EFe) 51.99% 15.62, 72.68 AdjustedDirectly Adjusted RR 1.325 0.7999, 2.1951 Taylor series MH Adjusted RR 1.315 0.791, 2.186 Taylor series Directly Adjusted RD 2.048% -6.604, 10.70 Taylor series Breslow-Day test for interaction of Risk Ratio over strata: chi square= 0.05771 p=0.8102 p greater than 0.05 does not suggest interaction. Adjusted RR can be used. Breslow-Day test for interaction of Risk Difference over strata: chi square= 1.182 p=0.2783 p greater than 0.05 does not suggest interaction. Adjusted RD can be used