Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

A critical parameter in the design of bioreactors is the maximum shear stress experienced by cells while in the reactor. If the shear stress is

A critical parameter in the design of bioreactors is the maximum shear
stress experienced by cells while in the reactor. If the shear stress is too high, the cells
will be torn apart or lysed. An example of a common biomedical device in which the
shear stress must be controlled is a blood oxygenator used clinically for heart/lung bypass
operations. Hemolysis can occur if red blood cells adhere to the wall of the device and
are subjected to high shear stresses.
Consider a blood oxygenator in which steady laminar flow of blood is directed through a
parallel membrane separated by a distance of d. What is the shear stress at the membrane
surface in terms of the average flow velocity, V. Assume that the blood is a Newtonian
fluid with viscosity and that the semi-permeable membranes can be modeled as infinite
planes. The geometry is depicted below:
image text in transcribed

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Molecular Engineering Thermodynamics

Authors: Juan J. De Pablo, Jay D. Schieber

1st Edition

0521765625, 9780521765626

More Books

Students also viewed these Chemical Engineering questions