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A critical reaction in the production of energy to do work or drive chemical reactions in biological systems is the hydrolysis of adenosine triphosphate, ATP,
A critical reaction in the production of energy to do work or drive chemical reactions in biological systems is the hydrolysis of adenosine triphosphate, ATP, to adenosine diphosphate, ADP, as described by the reaction
ATP(aq)+H2O(l)ADP(aq)+HPO24(aq)ATP(aq)+H2O(l)ADP(aq)+HPO42(aq)
for which rxn=30.5 kJ/mol at 37.0 C and pH 7.0. Calculate the value of rxn in a biological cell in which [ATP]=5.0 mM, [ADP]=0.70 mM,[ADP]=0.70 mM, and [HPO24]=5.0 mM.
rxn=_________kJ/mol
Is the hydrolysis of ATP spontaneous under these conditions?
Yes or no?
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