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A crossover trial is a type of experiment used to compare two drugs. Subjects take one drug for a period of time, then switch to

A crossover trial is a type of experiment used to compare two drugs. Subjects take one drug for a period of time, then switch to the other. The responses of the subjects are then compared using matched-pair methods. In an experiment to compare two pain relievers, seven subjects took one pain reliever for two weeks, then switched to the other. They rated their pain level from

1

to

10

, with larger numbers representing higher levels of pain. The results are listed below. Can you conclude that the mean pain level differs with drug B? Let

1

represent the mean pain level with drug A and

=d12

.Use the

=0.01

level and the

P

-value method with the TI-84 Plus calculator.

Subject
1 2 3 4 5 6 7
Drug A 5 6 6 4 7 7 7
Drug B 3 3 1 5 3 4 4

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Part:0 / 4

0 of 4 Parts Complete

Part 1 of 4

(a) State the appropriate null and alternate hypotheses.

(b) Compute the P value.

(c) Determine whether to reject H0

.

:H0
:H1

This is a (Choose one) test.

d

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