Question
A crossover trial is a type of experiment used to compare two drugs. Subjects take one drug for a period of time, then switch to
A crossover trial is a type of experiment used to compare two drugs. Subjects take one drug for a period of time, then switch to the other. The responses of the subjects are then compared using matched-pair methods. In an experiment to compare two pain relievers, seven subjects took one pain reliever for two weeks, then switched to the other. They rated their pain level from1to10,with larger numbers representing higher levels of pain. The results are listed below. Can you conclude that the mean pain levelis more with drug B?Let1 represent the mean pain level with drug A andd = 1 - 2.Use the=0.01level and theP-value method with the table.
Subject
1 2 3 4 5 6 7
Drug A 5 2 1 7 4 3 7
Drug B 7 6 6 7 6 6 7
- State the appropriate null and alternate hypotheses.
- Determine what kind of hypothesis test this is. (Right-tailed, left-tailed, or two-tailed).
- Compute the test statistic. Round the answer to three decimal places.
- How many degrees of freedom are there, using the simple method?
- Estimate theP-value. Fill in the correct blank. P (blank), P > (blank), (blank) < P (blank).
- Determine whether to rejectH0.
- State a conclusion.
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