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A flow perfusion bioreactor is being used to provide shear flow to mesenchymal stem cells seeded into a cylindrical polylactic acid scaffold. The scaffold
A flow perfusion bioreactor is being used to provide shear flow to mesenchymal stem cells seeded into a cylindrical polylactic acid scaffold. The scaffold has a radius of 15 mm, a porosity of 65%, and an average pore diameter of 307.9 um. If a volumetric flow rate of 12 mm3/s is applied and the dynamic viscosity of the perfusion media is 6.9 x 10-4 Pa's, estimate the wall shear stress imparted to the cells at the scaffold surface.
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Fundamentals of Heat and Mass Transfer
Authors: Incropera, Dewitt, Bergman, Lavine
6th Edition
978-0470055540, 471457280, 470881453, 470055545, 978-0470881453, 978-0471457282
