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A new device is being developed for measurement of plasma glucose concentration intended to cover the range 6 3 1 9 7 mg / dL

A new device is being developed for measurement of plasma glucose concentration intended
to cover the range 63197 mg/dL. A prototype for the device has been completed, with an
output display indicating the estimated concentration level, denoted . To calibrate the
device, the true concentration, denoted , is manipulated experimentally and the indicated
values are recorded.
A. In a first experiment, the true concentration is set to a fixed value of 130 mg/dL and 10
repeated measurements of the indicated concentration are recorded:
=[130.79,128.64,122.73,132.52,130.5,...
138.14,124.36,129.15,126.08,131.69] mg/dL
i. Compute the devices bias error and precision error.
ii. If it is determined that the bias and precision error computed above are of a fixed
magnitude across the devices operating range, then given an indicated value of 152
mg/dL, what would be its 95% confidence interval?
B. In another similar device, it is found that there is a bias error that varies over the input
range and that differs depending on whether the input is ascending versus descending.
It is determined that the best fitting polynomial of the input-output curve (i.e., vs.) is
given by
=0.0221.2+300/
when the true concentration is ascending, and
=0.022+9.2196.44/
when the true concentration is descending. Compute the % hysteresis of the device.

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