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A randomized controlled trial was conducted to determine whether treatment with daily aspirin was more effective than placebo at preventing myocardial infarction (MI) (within 5

A randomized controlled trial was conducted to determine whether treatment with daily aspirin was more effective than placebo at preventing myocardial infarction (MI) (within 5 years). A total of 140 out of 11,140 subjects in the aspirin group experienced an MI, while 240 out of 11,040 subjects in the placebo group experienced an MI. The relative risk of MI comparing aspirin to placebo was calculated to be 0.58, and its 95% confidence interval ranged from 0.47 to 0.71. Which of the following can be concluded from these results?

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On average, the risk of MI among subjects who used aspirin was 0.58 times the risk of MI among those on placebo.
On average, aspirin reduced the risk of MI in this population by 58% when compared to placebo.
Aspirin is almost certainly harmful to this population.
Compared to placebo, aspirin did not reduce the risk of MI by a statistically significant amount.

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