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A single bolus injection of chloroquine at 20 mg/kg was given to a 120 lb woman. Urine samples were collected and assayed for drug; the

A single bolus injection of chloroquine at 20 mg/kg was given to a 120 lb woman. Urine samples were collected and assayed for drug; the results are shown in the table below.

Time (hours) Drug in Urine (mg)
0.5 140
1 104
2 133
4 108
7 36
11 6

Use the data in this table to answer the following three questions.

What is the renal excretion rate constant?

What is the total excretion rate constant?

What is the rate constant for excretion from all non-renal sources?

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