Question
A spherical pill of drug A, 3 cm in diameter, is taken orally into the stomach acid, where it is subjected to a stream
A spherical pill of drug A, 3 cm in diameter, is taken orally into the stomach acid, where it is subjected to a stream of fluid of a constant velocity of 1.4m/s. A slowly dissolves into the acid with a solubility of 1.203x10 3 mol/cm. The diffusivity of A in stomach acid (DAB) is 9.907x10-6 cm/sec, and the acid has a viscosity of 2.378 907x10-5 m/sec. a. Determine the initial dissolution rate of the drug in mol/m-sec? b The integral equation to find the time it will take for the drug pill to shrink in terms of its radius? As the pill shrinks, its diameter is decreasing, which in turn affects the Reynolds and Sherwood numbers.
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Physics Principles with Applications
Authors: Douglas C. Giancoli
7th edition
978-0321869111, 321625927, 9780321733627, 321869117, 9780321625922, 321733622, 978-0321762429
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