A study compared doses of a drug on female rats' activity levels in a maze. A sample of 91 rats were

selected, and randomized such that 21 rats received the Control Dose, 25 received Low Dose, 24 received

Medium Dose, and 21 received High Dose. Each rat's activity levels were observed at 4 time points after

dosing (15, 30, 45, and 60 minutes).

Hint: There are a total of 21+25+24+21=91 rats in the study.

a. Write out the statistical model.

b. Complete the following ANOVA table. The dose and time means are given in the second table.

c. Obtain a 95% Confidence Interval for the difference between the Means for High Dose and

Control.

Source df SS MS F F(0.05) Significant?

Dose

Rat(Dose) 176677 #N/A #N/A #N/A

Time

Dose*Time 2161

Error2 #N/A #N/A #N/A

Total 465319 #N/A #N/A #N/A #N/A

Treat N_dose Time 1 Time 2 Time 3 Time 4 Mean

Control 21 165.9 136.3 121.4 103.4 131.8

Low Dose 25 167.8 148.4 123.7 118.4 139.6

Mid Dose 24 168.3 140.3 117.2 109.8 133.9

High Dose 21 184.4 156.2 136.3 122.7 149.9

Sum/Mean 91 171.3 145.3 124.4 113.7 138.7