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A study for the treatment of patients with HIV-1 was a randomized, controlled, double-blind study that compared the effectiveness of ritonavir-boosted darunavir (rod), the drug
A study for the treatment of patients with HIV-1 was a randomized, controlled, double-blind study that compared the effectiveness of ritonavir-boosted darunavir (rod), the drug currently used to treat HIV-1, with dorovirine, a newly developed drug Of the 386 subjects taking ritonavir-boosted darunavir, 306 achieved a positive result. Of the 386 subjects taking dorovirine, 325 achieved a positive result. Complete parts (a) and (b). a. Find the sample percentage of subjects who achieved a positive outcome in each group. The sample percentage of subjects who achieve a positive outcome with ritonavir-boosted darunavir is %. The sample percentage of subjects who achieve a positive outcome with dorovirine is %. Round to two decimal places as needed.) b. Perform a hypothesis test to test whether the proportion of patients who achieve a positive outcome with the current treatment (ritonavir-boosted darunavir) is less than the proportion of patients who achieve a positive outcome with the new treatment (dorovirine). Use a significance level of 0.01. Analyze the results and determine if dorovirine is a more effective treatment for HIV-1 than ritonavir-boosted darunavir. Consider population 1 to be the ritonavir-boosted darunavir with the proportion of positive outcomes p, and population 2 to be the dorovirine with the proportion of positive outcomes p2. What are the null and alternative hypotheses for the hypothesis test? O A. Ho: P1 > P2 O B. Ho: P1 = P2 O C. Ho: P1 P2 Ha: P1 = P2 OD. HO: P1 # P2 OE. HO: P1 = P2 OF. HO: P1 = P2 Ha : P1 = P2 Ha: P1 # P2 Ha: P1
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