A study is conducted to assess the relationship between substance use during the first trimester of pregnancy and miscarriage. A sample of 410 women self-reported substance use status at the end of their first trimester and were followed up until the end of pregancy. The incident of miscarrige was self-reported if occurred. Compute the population attributable risk of miscarriage for women with substance use issues. (The data are shown below.)

	Free of Miscarriage	Miscarrige
No Substance Use	148	21
Substance Use	196	45

A. 0.124

B. 0.228

C. 0.839

D. 0.772