A study is designed to investigate whether there is a difference in response to various treatments in patients with Rheumatoid arthritis. The outcome is the patient's self-reported effect of treatment. The data are shown below. Is there a significant difference in effect of treatment? Run the test at a 5% level of significance.

Symptoms

Worsened

No Effect

Symptoms Improved

Total

Treatment 1

22

14

14

50

Treatment 2

14

15

21

50

Treatment 3

9

12

29

50