A woman is hospitalizedin the eveningfor complications from aminor surgical procedure. Her doctorprescribes the antibiotic gentamicin for treatment of a persistent infection.Since she has anintravenous catheter in place, gentamicin is to be given via the catheterat oneinitial dose of 100mgthat evening followed by maintenance doses of 80 mg infusedthree timesdaily for a period of fivedays. The woman weighs 135 pounds and theparenteralformulation contains10 mg/ml ofgentamicin.

(a)What volume of gentamicin solution should be administered for the first dose?

(b)What volume should be given for each of the maintenance doses?

(c)It turns out that this woman is a pharmacy student and she remembers from classthat therecommended daily dose rate for adults with normal kidney function (which she has) is 3to 5mg/kg/day. Is she receiving an appropriatemaintenancedose(yes or no) and explain therationale foryour answer.