(A) You want to design a polymeric controlled-release delivery system for a small-molecule, hydrophobic drug that has a daily dose of 100 g and should deliver the drug at a very consistent rate for five years.

(B) You want to design a polymeric controlled-release delivery system for a small-molecule, hydrophobic drug that has a daily dose of 10 g and should deliver the drug at a relatively consistent rate for one month.

For each of these scenarios,

- what kind of delivery system will you design and why?

-Will you use a reservoir, matrix or hydrogel design?

-Will you use a degradable or non-degradable polymer?

-Will you use a macroscopic device, a microparticle or a nanoparticle design?