Accounting SEA aims to prepare students for their active working life after university in all capacities: as researchers, as employees and as entrepreneurs. With the global knowledge economy, SEA sees a growing need for innovative and flexible entrepreneurs and intrapreneurs. They see new emerging structures where businesses are established, sold, closed or continued in new contexts. The notion of a life-time business which is established by young entrepreneurs, consolidated through their mature years and eventually inherited and continued by their sons and daughters now belongs to the long-gone industrial society. Nowadays, entrepreneurship is about self-realisation, about growing, changing, seizing new opportunities and continuously meeting new challenges

61 Can carvedilol be used in an elderly patient who developed left ventricular failure after a very recent myocardial infarction, or should it wait until the condition becomes stable?

62 I have seen some patients with chronic rheumatic heart disease with no obvious evidence of rheumatic fever (i.e. they could not recall if there was an episode of severe infection with subsequent fever and joint pain). So, actually, how is chronic rheumatic heart disease diagnosed?

63 If a young patient presents with hemiparesis and rheumatic atrial fibrillation and is already on oral anticoagulant, with an international normalized ratio (INR)

3 and a normal computed tomography (CT) scan done 2 hours after onset, should he receive heparin for prophylaxis against further embolism? Should aspirin be combined with oral anticoagulant later, or should target INR be increased? 64 When treating mitral stenosis using a balloon valvotomy, how come no thrombus develops at the site of the atrial septum or at the separated commissure of the valve leaflets?

65 Why does a mitral stenosis produce a loud S1?

66 Why is the mitral valve more affected than any other valve in the heart in most valvular diseases?

67 What is William's syndrome (supravalvular obstruction)? Why does hypercalcaemia occur with this syndrome?

68 Kindly tell me all the causes postulated for the collapsing pulse seen in aortic regurgitation.

69 Does pulmonary stenosis cause pulmonary hypertension?

70 Under what conditions would a pulsatile liver be found and what is its clinical significance?