Answered step by step
Verified Expert Solution
Question
1 Approved Answer
An investigator measured height in 100 pairs of monozygotic and 100 pairs of dizygotic twins. The twins were all aged between twelve and eighteen years
An investigator measured height in 100 pairs of monozygotic and 100 pairs of dizygotic twins. The twins were all aged between twelve and eighteen years of age. The estimated correlation between MZ twin pairs was rmz = 0.8, and the estimated correlation between DZ twin pairs was roz = 0.6. a. Estimate the proportion of variance explained by additive genetic (VA), dominance genetic (VD), common environmental (VC) and unique environmental (VE) sources of variation based on these correlations. (2 marks) b. The investigators decided to statistically control for the effect of age on height before recalculating the MZ and DZ intra-pair correlations. What effect do you think this analysis would have on estimates of the variance components calculated above and why? (2 marks) C. Explain the equal environments assumption (EEA) in this context and what violation of the EEA would likely do. (3 marks) An investigator measured height in 100 pairs of monozygotic and 100 pairs of dizygotic twins. The twins were all aged between twelve and eighteen years of age. The estimated correlation between MZ twin pairs was rmz = 0.8, and the estimated correlation between DZ twin pairs was roz = 0.6. a. Estimate the proportion of variance explained by additive genetic (VA), dominance genetic (VD), common environmental (VC) and unique environmental (VE) sources of variation based on these correlations. (2 marks) b. The investigators decided to statistically control for the effect of age on height before recalculating the MZ and DZ intra-pair correlations. What effect do you think this analysis would have on estimates of the variance components calculated above and why? (2 marks) C. Explain the equal environments assumption (EEA) in this context and what violation of the EEA would likely do
Step by Step Solution
There are 3 Steps involved in it
Step: 1
Get Instant Access to Expert-Tailored Solutions
See step-by-step solutions with expert insights and AI powered tools for academic success
Step: 2
Step: 3
Ace Your Homework with AI
Get the answers you need in no time with our AI-driven, step-by-step assistance
Get Started