App Note Title: Analysis of Flavonoids in Juices with the ACQUITY QDa Detector

1. This technique uses UV/Vis and MS for detection. What other technique would provide higher sensitivity for the molecules in question compared to UV/Vis? Why are these molecules well suited for that technique? (2 marks)
2. Sinensetin and tangeretin have the same m/z. What does this mean and why is is this not a problem for this particular analysis (2 marks)
3. Nobiletin and Tetramethoxyscutellarein have overlapping peaks in this chromatographic method. Is this a problem for UV/Vis? Why, what will be impacted? Why is this not a problem for this particular analytical method? (3 marks)
4. What does SIR mean in the context of this application note? (1 mark)