Question
Apply Lipinskis Rules to the structure of terfenadine. What does your analysis tell you about the suitability of terfenadine as a drug? (5 marks) 'N'
Apply Lipinski’s Rules to the structure of terfenadine. What does your analysis tell you about the suitability of terfenadine as a drug? (5 marks)
'N' Ph. OH HO Ph Terfenadine 4 Molecular Weight: 471.67 LogP: 3.22
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Organic Chemistry A Short Course
Authors: Harold Hart, Christopher M. Hadad, Leslie E. Craine, David J. Hart
13th edition
1111425566, 978-1111425562
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