As a result of the therapeutic misconception, subjects often "deny the possibility that there may be major disadvantages to participating in clinical research that stem from the nature of the research process itself." Paul S. Appelbaum et al., False Hopes and the Best Data: Consent to Research and the Therapeutic Misconception, 17 HASTINGS CENTER REP., April 1987, at 20.

https://www.jstor.org/stable/3562038?origin=crossref

What explains the existence of the therapeutic misconception? What steps can researchers and IRBs take to address it? Can the therapeutic misconception be completely overcome? If not, what are the implications for our system of research regulation?