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Question 49 There have been a number of recent publications concerning aspirin versus warfarin trials. Would you recommend prescribing warfarin for secondary prevention of coronary heart disease in patients suffering from their first myocardial infarction (MI)? Question 50 Is it true that in future the ApoA : ApoB ratio will be used to predict the risk of coronary artery disease more efficiently than low-density lipoprotein (LDL)? Question 51 What is the exact link between C-reactive protein (CRP) and coronary artery disease? Question 52 In angina pectoris, why does the chest pain get radiated to the left side, i.e. left arm and back? Question 53 Please explain why thrombolytic therapy is not indicated in cases of unstable angina and non-ST-segment elevation myocardial infarctions (nSTE-MI) despite the fact that both nSTE-MI and ST-elevated MI (STEMI) are caused by a thrombus for which thrombolytic therapy is highly indicated? Could it be true that, in the case of unstable angina and nSTE-MI has a higher incidence of intracranial haemorrhage than in the case of ST-segment elevation MI? Question 54 Doesn't the term 'acute coronary syndrome' include unstable angina, non ST-segment elevation myocardial infarctions and ST-elevated MI (STEMI)? Question 55 Kindly mention the indications for clopidogrel in acute coronary syndrome (ACS). Should it be used along with aspirin or alone if the latter is contraindicated? Are there any studies that combine both with either low-molecular-weight heparin (LMWH) or unfractionated heparin? How long should clopidogrel be continued? Question 56 What role do IV fluids play in the management of acute inferior wall myocardial infarction? Question 57 Is there any benefit in combining aspirin with clopidogrel in post-MI angina and ischaemic stroke? A MATCH trial showed this combination 13 Cardiovascular disease 126 not to be of benefit - would you therefore recommend we stop using this combination in our hospital unit?