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(b) The diagram below itlustrates the acetylcholine esterase active site that contains a catalytic triad of three amino acids, serine, histidine and glutamate. The enzyme

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(b) The diagram below itlustrates the acetylcholine esterase active site that contains a catalytic triad of three amino acids, serine, histidine and glutamate. The enzyme catalyses the hydrolysis of the natural substrate acetylcholine, also shown. PAGE 7 OF 12 SEE NEXT PAGE 5CCC0060 MAY 2021 Acetylcholine esterase active site (i) What are the catalytic functions of the three amino acids? (3 marks) (ii) Suggest a way that the enzyme could achieve selectivity for acetylcholine. (3 marks) (iii) Using curly arrows, propose a mechanism for the hydrolysis reaction of acetylcholine. (7 marks) (iv) Using your mechanism in (iii), suggest why the following molecule acts as a potent nerve agent

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