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Based on the readings, 1. The exact neurochemical factors that contribute to major depression remain unknown. 2. Major depression is caused by a down-regulation of

Based on the readings,

1. The exact neurochemical factors that contribute to major depression remain unknown.

2. Major depression is caused by a down-regulation of serotonin receptors

3. Major depression is caused by too little serotonin in the brain

4. Major depression is caused by too much serotonin in the brain

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