Because of the importance of anchor stores to a mall's success, small retailers often try to secure certain clauses in their lease agreements that protect them if anchor stores "go dark" - meaning, they close. A vacant ("dark") anchor store space is a sure sign that a mall is struggling and an indication that a smaller retailer could be in an undesirable location if the situation doesn't turn around.

11 What is the significance of the thyroid-releasing horomone (TRH) test in differentiating various causes of hypothyroidism?

12 Is retention of urine/incomplete voiding related to hypothyroidism? If so, how?

13 It is stated that a little overtreatment might be required for hypothyroidism, i.e. slightly raised thyroxine (T4) and suppressed thyroid-stimulating hormone (TSH). Is the clinical improvement the best criteria or is there an optimum/maximum level that one should watch out for when monitoring TSH and T4?

14 Why is thyroid-stimulating hormone (TSH) normal or increased in patients with peripheral resistance to tri-iodothyronine (T3) and thyroxine (T4)? The thyroid hormone levels are high in these patients, so the TSH should drop lower: why doesn't it?

15 Thyroxine is a peptide hormone used to treat thyroid deficiency and other thyroid disorders. It is taken orally. Peptides are broken down into amino acids before being absorbed. What factors cause the thyroxine to remain stable in the digestive tract so that it is absorbed without being digested?

16 1. Does the absence of bradycardia exclude hypothyroidism? 2. How often is hypothyroidism accompanied by bradycardia?

17 Should patients with hypo- or hyperthyroidism be given iodine supplements?

18 Is Hashimoto's thyroiditis associated with dementia?

19 Please explain the causes of, and suggest recommended treatments for, euthyroid and hypothyroid states.

20 What is the role of propranolol in the management of a 35-year-old male thyrotoxic patient who is also hypertensive?