Business law stly upon the younger, inexperienced engineers fresh out of college. With the adoption of this corporate strategy, Parks Corporation administered a new wage and salary program that included job upgrading. Gary was promoted to senior scientist, responsible for all R&D activities performed in the mechanical engineering department. Gary had distinguished himself as an outstanding production engineer during the past several years, and management felt that his contribution could be extended to R&D as well. In January 1978, Parks Corporation decided to compete for Phase I of the Blue Spider Project, an R&D effort that, if successful, could lead into a $500 million program spread out over 20 years. The Blue Spider Project was an attempt to improve the structural capabilities of the Spartan missile, a short-range tactical missile used by the Army. The Spartan missile was exhibiting fatigue failure after six years in the field. This was three years less than what the original design specifications called for. The Army wanted new materials that could result in a longer life for the Spartan missile.

121 A 25-year-old woman, pregnant in her second trimester, starts to experience chorea and bilateral ankle arthralgia but has no past history of rheumatic chorea. In the first hour, her erythrocyte sedimentation rate is 70. Could this be no more than chorea gravidarum?

122 Is valproate as equally effective as haloperidol in the treatment of chorea, in particular rheumatic chorea?

123 Does a lesion of Guillain-Mollaret's triangle in the brain stem cause a type of myoclonus other than symptomatic palatal myoclonus?

124 1. In West's syndrome, after the fits have been suppressed, for how long should treatment with adrenocorticotrophic hormone (ACTH) continue? 2. Does complete suppression of resistant infantile myoclonic jerks by ACTH characterize West's syndrome?

125 Are anticholinergics the first line of treatment for primary torsion dystonia?

126 Can multiple sclerosis (MS) be associated with lack of vitamin D, lack of sunlight or low fish/cod-liver oil in the diet? By looking at the epidemiology (none at the equator; more outside 40 latitude, both north and south; less on top of Swiss mountains than in the Swiss valleys; more in fishing coastal towns and in Eskimos) this seems to be very important. Vitamin D modulates the immune system and active vitamin D given to rats with experimental MS (acute encephalomyelitis) lowers the monocyte count in cerebrospinal fluid (CSF) by 90% in 72 hours with return of power to their limbs. Japanese MS patients who ate plenty of fish were found to have vitamin-D-receptor pleomorphism. The staple grains and cereals (wheat, barley, oats) eaten in Scandinavian and northern European countries contain phytic acid, which blocks vitamin D absorption, and rice is the only cereal free of phytic acid. Are there any studies where low vitamin D levels in blood are associated with MS relapse?

127 What are the diagnostic criteria of 'definitive' multiple sclerosis (MS) - as taught to a medical student? We have found different information from different sources.

128 How reliable is a CT-brain scan with contrast in showing MS lesions as enhancing lesions in the presence of a contraindication to use MRI?

129 Is magnetic resonance (MR) spectroscopy of value in differentiating multiple sclerosis from cerebral autosomal dominant arteriopathy with subcortical infarctions (CADASIL)?

130 Does hemiplegia due to multiple sclerosis present with hemiparesis rather than dense hemiplegia (which is more characteristic of a stroke)? Other than age, what are the clinical signs that would help differentiate between the two?